Cut and peel butternut squash into bite sized pieces, about 1/2" cubes.
Whisk together oil, paprika, garlic powder, salt, and pepper in a large bowl. Add butternut squash cubes and toss in marinade to coat all squash pieces.
Add the squash to air fryer basket (if you have a small air fryer, cook it in two batches). Try to keep the squash in a single layer for more even cooking.
Air Fry at 380
Continue to air fry at 380